改良整塊切除術是一種混合技術,涉及先將膀胱腫瘤的外生部分分塊切除,然後對腫瘤基底進行整塊切除。在本研究中,我們將探討改良整塊切除術對腫瘤大小≥3cm的膀胱腫瘤患者的療效。
適應症:Bladder Cancer、Bladder Neoplasm、Bladder Tumor
收案條件
納入條件
- Age 18 to 80 years old with informed consent
- Bladder tumours with maximal dimension of ≥ 3cm
排除條件
- Bladder tumour detected during intravesical Bacillus Calmette-Guerin therapy (These patients warrant more aggressive treatment, i.e. radical cystectomy)
- Estimated glomerular filtration rate of \<60mL/min.
- Presence of clinically significant cardiovascular disease (History of acute myocardial infarction, presence of uncontrolled angina within 3 months before screening, New York Heart Association Class III or IV congestive heart failure, presence of ventricular arrhythmias, or presence of second-degree or third-degree heart block)
- Presence of GOLD Stage III or IV chronic obstructive pulmonary disease
- History of bleeding disorder or use of anti-coagulant
- Presence of other active malignancy
- ECOG performance status ≥ 2 (Ambulatory and capable of all self care but unable to carry our any work activities. Confined to bed or chair less than 50% of waking hours)
- Pregnancy
- Presence of metallic foreign body or implant which is not MRI compatible
- Known history of claustrophobia
收案條件維持 ClinicalTrials.gov 原始英文登錄資料,實際收案資格以研究團隊的正式評估與受試者同意書為準。資料來源:ClinicalTrials.gov,每兩週自動更新,最後同步:2026年10月8日。