已完成 NCT04081246

經尿道改良整塊切除術治療大型膀胱腫瘤

膀胱癌/泌尿道上皮癌不適用III 期

改良整塊切除術是一種混合技術,涉及先將膀胱腫瘤的外生部分分塊切除,然後對腫瘤基底進行整塊切除。在本研究中,我們將探討改良整塊切除術對腫瘤大小≥3cm的膀胱腫瘤患者的療效。

適應症:Bladder Cancer、Bladder Neoplasm、Bladder Tumor

收案條件

納入條件

  • Age 18 to 80 years old with informed consent
  • Bladder tumours with maximal dimension of ≥ 3cm

排除條件

  • Bladder tumour detected during intravesical Bacillus Calmette-Guerin therapy (These patients warrant more aggressive treatment, i.e. radical cystectomy)
  • Estimated glomerular filtration rate of \<60mL/min.
  • Presence of clinically significant cardiovascular disease (History of acute myocardial infarction, presence of uncontrolled angina within 3 months before screening, New York Heart Association Class III or IV congestive heart failure, presence of ventricular arrhythmias, or presence of second-degree or third-degree heart block)
  • Presence of GOLD Stage III or IV chronic obstructive pulmonary disease
  • History of bleeding disorder or use of anti-coagulant
  • Presence of other active malignancy
  • ECOG performance status ≥ 2 (Ambulatory and capable of all self care but unable to carry our any work activities. Confined to bed or chair less than 50% of waking hours)
  • Pregnancy
  • Presence of metallic foreign body or implant which is not MRI compatible
  • Known history of claustrophobia

收案條件維持 ClinicalTrials.gov 原始英文登錄資料,實際收案資格以研究團隊的正式評估與受試者同意書為準。資料來源:ClinicalTrials.gov,每兩週自動更新,最後同步:2026年10月8日。