本研究探討 HMGB1 的區室化分佈及 O-GlcNAcylation 如何調控癌症中的炎症訊號傳導、自噬及免疫逃逸。我們的研究聚焦於 HMGB1,此為炎症及免疫調控的關鍵介質。
適應症:Esophageal Squamous Cell Carcinoma (ESCC)
收案條件
納入條件
- Age ≥ 18 years.
- Histologically confirmed ESCC
- Able to provide written informed consent.
- Able to comply with study procedures.
排除條件
- Withdrawal of consent.
- Irreversible coagulation disorders preventing clinically indicated biopsies.
- With other co-existing malignancy
收案條件維持 ClinicalTrials.gov 原始英文登錄資料,實際收案資格以研究團隊的正式評估與受試者同意書為準。資料來源:ClinicalTrials.gov,每兩週自動更新,最後同步:2026年10月8日。