即將開始 NCT07615556

ctDNA突變與甲基化狀態用於可疑肺結節患者肺癌早期檢測

肺癌不適用I 期II 期

肺癌在亞洲常見,其流行病學及治療方式與西方國家的肺癌有所不同。肺癌可以早期發現,但大多數早期肺癌在影像上表現為具有可疑特徵的肺結節。對具有可疑肺結節的受試者進行檢查及監測是一項臨床難題。

適應症:Lung Nodules、Lung Cancer Screening、Suspected Lung Cancer

收案條件

納入條件

  • Age 45 - 80 years;
  • Suspicious lung nodules (\> 0.5 - 30mm in longest diameter, non-calcified) found within the past six months, or if PET scan has been done before, the specific uptake value (SUV) should be more than 1

排除條件

  • Age \< 45 or \> 80;
  • Lung nodules of \< 0.5 cm in longest diameter, or with calcification seen in imaging;
  • Known lung cancer or lung metastasis before, or history of extra-pulmonary cancer;
  • Active tuberculosis;
  • Clinical unstable conditions including untreated ischemic heart disease or arrhythmia, uncontrolled airway disease;
  • Unwillingness to undergo invasive investigation like bronchoscopy;
  • Unable to provide informed written consent.

收案條件維持 ClinicalTrials.gov 原始英文登錄資料,實際收案資格以研究團隊的正式評估與受試者同意書為準。資料來源:ClinicalTrials.gov,每兩週自動更新,最後同步:2026年10月8日。