患有癌症的老年患者由於合併症、功能障礙和老年綜合症,面臨較高的嚴重化療相關毒性風險。綜合老年評估(GA)可以識別脆弱性並指導量身定制的管理,但由於時間和資源限制,常規實施具有挑戰性。 這項試點隨機對照試驗評估患者自我報告的可行性及初步療效,r
適應症:Cancer、Geriatric Syndrome、Frailty、Chemotherapy Toxicity
收案條件
納入條件
- Aged 65-74 years with impaired G8 questionnaire score, or aged 75 years or older.
- Diagnosis of lung cancer, colorectal cancer, breast cancer, gastric cancer, or uterine cancer with histological confirmation or radiological diagnosis.
- Scheduled to receive a new systemic anti-cancer treatment that includes chemotherapy. Any line of cytotoxic chemotherapy is allowed, including regimens combined with targeted therapy or immunotherapy, provided the planned regimen is expected to last at least 3 months.
- ECOG Performance Status 0-2.
- Able to communicate in English or Chinese.
- Able to provide valid informed consent.
排除條件
- Planned treatment with radiotherapy alone.
- Planned systemic treatment given concurrently with radiotherapy.
- Planned treatment with hormonal therapy alone (e.g., tamoxifen, aromatase inhibitors, LHRH agonists).
- Planned surgery within the next 3 months.
- Life expectancy less than 3 months.
- Dementia or otherwise mentally unfit to provide informed consent.
收案條件維持 ClinicalTrials.gov 原始英文登錄資料,實際收案資格以研究團隊的正式評估與受試者同意書為準。資料來源:ClinicalTrials.gov,每兩週自動更新,最後同步:2026年10月8日。