進行中(不再收案) NCT07485634

以風險為本的老年評估驅動管理於開始化療的老年患者

肺癌乳癌大腸直腸癌胃癌子宮頸癌/婦癌不適用

患有癌症的老年患者由於合併症、功能障礙和老年綜合症,面臨較高的嚴重化療相關毒性風險。綜合老年評估(GA)可以識別脆弱性並指導量身定制的管理,但由於時間和資源限制,常規實施具有挑戰性。 這項試點隨機對照試驗評估患者自我報告的可行性及初步療效,r

適應症:Cancer、Geriatric Syndrome、Frailty、Chemotherapy Toxicity

收案條件

納入條件

  • Aged 65-74 years with impaired G8 questionnaire score, or aged 75 years or older.
  • Diagnosis of lung cancer, colorectal cancer, breast cancer, gastric cancer, or uterine cancer with histological confirmation or radiological diagnosis.
  • Scheduled to receive a new systemic anti-cancer treatment that includes chemotherapy. Any line of cytotoxic chemotherapy is allowed, including regimens combined with targeted therapy or immunotherapy, provided the planned regimen is expected to last at least 3 months.
  • ECOG Performance Status 0-2.
  • Able to communicate in English or Chinese.
  • Able to provide valid informed consent.

排除條件

  • Planned treatment with radiotherapy alone.
  • Planned systemic treatment given concurrently with radiotherapy.
  • Planned treatment with hormonal therapy alone (e.g., tamoxifen, aromatase inhibitors, LHRH agonists).
  • Planned surgery within the next 3 months.
  • Life expectancy less than 3 months.
  • Dementia or otherwise mentally unfit to provide informed consent.

收案條件維持 ClinicalTrials.gov 原始英文登錄資料,實際收案資格以研究團隊的正式評估與受試者同意書為準。資料來源:ClinicalTrials.gov,每兩週自動更新,最後同步:2026年10月8日。