患有癌症的老年患者由于合并症、功能障碍和老年综合症，面临较高的严重化疗相关毒性风险。综合老年评估（GA）可以识别脆弱性并指导量身定制的管理，但由于时间和资源限制，常规实施具有挑战性。 这项试点随机对照试验评估患者自我报告的可行性及初步疗效，r
适应症：Cancer、Geriatric Syndrome、Frailty、Chemotherapy Toxicity
入组条件
纳入标准
- Aged 65-74 years with impaired G8 questionnaire score, or aged 75 years or older.
- Diagnosis of lung cancer, colorectal cancer, breast cancer, gastric cancer, or uterine cancer with histological confirmation or radiological diagnosis.
- Scheduled to receive a new systemic anti-cancer treatment that includes chemotherapy. Any line of cytotoxic chemotherapy is allowed, including regimens combined with targeted therapy or immunotherapy, provided the planned regimen is expected to last at least 3 months.
- ECOG Performance Status 0-2.
- Able to communicate in English or Chinese.
- Able to provide valid informed consent.
排除标准
- Planned treatment with radiotherapy alone.
- Planned systemic treatment given concurrently with radiotherapy.
- Planned treatment with hormonal therapy alone (e.g., tamoxifen, aromatase inhibitors, LHRH agonists).
- Planned surgery within the next 3 months.
- Life expectancy less than 3 months.
- Dementia or otherwise mentally unfit to provide informed consent.
入组条件维持 ClinicalTrials.gov 原始英文登记资料，实际入组资格以研究团队的正式评估与受试者知情同意书为准。资料来源：ClinicalTrials.gov，每两周自动更新，最后同步：2026年10月8日。