由於證據不足,目前不建議對非吸煙者進行肺癌篩查。新興證據顯示,一等親家族史是亞洲非吸煙者罹患肺癌的強烈風險因素。在亞洲,資源匱乏是成功實施肺癌篩查的主要挑戰。人工智能(AI)是克服此資源限制的具前景工具。
適應症:Lung Cancer
收案條件
納入條件
- Patients are eligible to be included in the study only if all of the following criteria apply:
- Age 50-75 years old
- Non-smoker (defined as less than 100 cigarettes in lifetime)
- Having a first-degree family history of lung cancer
- Physically fit for curative treatment if early-staged lung cancer is found
- Able to provide written informed consent
- Consent to follow up visits and follow up CT scan if indicated
- Consent to blood taking for translational research
排除條件
- History of malignancy
- Smoking history (defined as more than 100 cigarettes in lifetime)
- Clinical symptoms suspicious for lung cancer e.g. haemoptysis, chest pain, weight loss
- Medical comorbidities that preclude curative treatment (surgery) for lung cancer, such as severe heart disease, acute or chronic respiratory failure, home oxygen therapy, bleeding disorder
- Pregnant ladies or ladies planning for conception
- History of tuberculosis or interstitial lung disease
- Pneumonia requiring antibiotic treatment within the last 12 weeks
- CT thorax or chest performed within 2 years (including LDCT, PET-CT, MRI thorax or suspicious of lung cancer)
- Unable or unwilling to provide written informed consent
收案條件維持 ClinicalTrials.gov 原始英文登錄資料,實際收案資格以研究團隊的正式評估與受試者同意書為準。資料來源:ClinicalTrials.gov,每兩週自動更新,最後同步:2026年10月8日。