聯合肝臟分隔及門靜脈結紮分期肝切除術（ALPPS）是一種新手術程序，可為計劃接受大範圍肝切除而殘餘肝臟較小的患者誘導快速肝臟再生。這是一項兩階段手術，第一階段包括門靜脈結紮及將右肝與左肝分離。
適應症：Liver Cancer
收案條件
納入條件
- Patients with a diagnosis of malignant liver tumor contemplating for extended right hepatectomy or right trisectionectomy
- Patient consent
- Age \>/= 18
- FLR/ESLV \</= 30%
- Indocyanine green clearance rate at 15 mins : \< 18%
- Platelet count \> 100x10\^9/L
- Child A cirrhosis (due to hepatitis B/C virus, or alcohol, or autoimmune disease)
- American Society of Anaesthesiology score \< 3
- Eastern Cooperative Oncology Group (ECOG) performance status 0-2
- Technical factors eligible for laparoscopic ALPPS
- single long-segment portal
排除條件
- Absence of consent
- Decompensated liver disease as indicated by the presence of ascites, varices and hepatic encephalopathy
- ECOG performance status \>/= 3
- Main portal vein thrombosis
- FLR/ESLV \> 30%
- Technical factors not eligible for laparoscopic ALPPS
- Short-segment right portal vein or early bifurcation of right anterior/posterior portal vein, or other portal vein anomalies
- Large tumor size with diameter \> 5 cm
- Intolerance to CO2 pneumoperitoneum
收案條件維持 ClinicalTrials.gov 原始英文登錄資料，實際收案資格以研究團隊的正式評估與受試者同意書為準。資料來源：ClinicalTrials.gov，每兩週自動更新，最後同步：2026年10月8日。