背景: 回顧性研究及統合分析顯示,與propofol為基礎的全靜脈麻醉(TIVA)相比,以吸入性麻醉為基礎的癌症手術後5年存活率有所降低。迄今為止,尚無前瞻性試驗發表評估麻醉技術對循環腫瘤細胞(CTC)、氧化應激及癌症手術後復發率的影響。
適應症:Solid Tumor、Carcinoma、Malignancy、Cancer
收案條件
納入條件
- patients coming for elective primary solid tumor resection for curative intent in Hong Kong Children's Hospital
- AND patients \> 5kg
- AND patients within age limit
排除條件
- Autoimmune / Chronic inflammatory diseases e.g. Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA) etc.
- Current Steroid therapy
- Surgery for tumour removal in the past year
- Allergy to Propofol
- intraoperative use of nitrous oxide
- Patient susceptible to Malignant Hyperthermia
- Patients / parents / legal guardians showing preference in anaesthetic techniques during recruitment process
收案條件維持 ClinicalTrials.gov 原始英文登錄資料,實際收案資格以研究團隊的正式評估與受試者同意書為準。資料來源:ClinicalTrials.gov,每兩週自動更新,最後同步:2026年10月8日。