背景: 回顾性研究及统合分析显示,与propofol为基础的全静脉麻醉(TIVA)相比,以吸入性麻醉为基础的癌症手术后5年生存率有所降低。迄今为止,尚无前瞻性试验发表评估麻醉技术对循环肿瘤细胞(CTC)、氧化应激及癌症手术后复发率的影响。
适应症:Solid Tumor、Carcinoma、Malignancy、Cancer
入组条件
纳入标准
- patients coming for elective primary solid tumor resection for curative intent in Hong Kong Children's Hospital
- AND patients \> 5kg
- AND patients within age limit
排除标准
- Autoimmune / Chronic inflammatory diseases e.g. Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA) etc.
- Current Steroid therapy
- Surgery for tumour removal in the past year
- Allergy to Propofol
- intraoperative use of nitrous oxide
- Patient susceptible to Malignant Hyperthermia
- Patients / parents / legal guardians showing preference in anaesthetic techniques during recruitment process
入组条件维持 ClinicalTrials.gov 原始英文登记资料,实际入组资格以研究团队的正式评估与受试者知情同意书为准。资料来源:ClinicalTrials.gov,每两周自动更新,最后同步:2026年10月8日。