進行中(不再收案) NCT03839914

評估傷口內 Vancomycin 粉末用於高風險患者的療效與安全性

皮膚癌不適用III 期IV 期

手術部位感染(SSI)並不罕見,尤其是在特定高風險組別,包括脊柱畸形及腫瘤(即轉移性脊柱手術)手術。目前已採用廣受認可的措施以減少手術部位感染,而近年局部使用 Vancomycin 粉末亦日益普及。

適應症:Spinal Deformity、Trauma、Spinal Tumor、Surgical Site Infection

收案條件

納入條件

  • Female or male adult with age ≥18 years
  • Undergoing open posterior spinal surgery with instrumentation indicated for spinal deformity, trauma and tumor
  • Able to understand the nature, scope and possible consequences of participation in the study
  • Appropriate voluntary written informed consent have been provided by patients

排除條件

  • Has been treated with antibiotics due to primary spinal infection (i.e. spondylodiscitis) within 1 year prior to surgery
  • Ongoing treatment with antibiotics for other infections
  • Undergoing minimally invasive surgery or anterior-only surgical approaches or deformity correction surgery for adolescent idiopathic scoliosis (inherent low-risk for surgical site infections18)
  • Undergoing decompression-only surgery for cervical spine, spinal deformity, trauma and tumors
  • Has known history of allergy to vancomycin, penicillin and other glycopeptides (teicoplanin)
  • Has history of vancomycin resistance
  • Pregnancy

收案條件維持 ClinicalTrials.gov 原始英文登錄資料,實際收案資格以研究團隊的正式評估與受試者同意書為準。資料來源:ClinicalTrials.gov,每兩週自動更新,最後同步:2026年10月8日。