传统上，经尿道标准切除（SR）膀胱肿瘤是以分块方式进行。经尿道整块切除（EBR）已被描述为膀胱肿瘤切除的替代手术技术。通过防止肿瘤碎裂并通过 EBR 标本的组织学评估确定肿瘤完全切除，我们假设 EBR 相比 SR 可减少疾病复发。
适应症：Bladder Cancer
入组条件
纳入标准
- Age ≥ 18 years old with informed consent
排除标准
- Bladder tumour base with maximal dimension of \>3cm (Anticipated difficulty in retrieving the specimen en bloc)
- Bladder tumour detected during intravesical BCG therapy (BCG failure warrants more aggressive treatment, i.e. radical cystectomy)
- Histological diagnosis other than NMIBC
- Presence or prior history of upper urinary tract malignancy
- ECOG performance status ≥ 3 (Confined to bed or chair more than 50% of waking hours)
- ASA III or above (Patient with severe systemic disease)
- History of bleeding disorder or use of anti-coagulants
- Pregnancy
- Presence of other active malignancy
- Life expectancy of less than one year
入组条件维持 ClinicalTrials.gov 原始英文登记资料，实际入组资格以研究团队的正式评估与受试者知情同意书为准。资料来源：ClinicalTrials.gov，每两周自动更新，最后同步：2026年11月5日。