The goal of this clinical trial is to learn whether SUPPORT+, a digital symptom monitoring and self-management mobile application, can improve health-related quality of life and clinical outcomes in adults with advanced cancer receiving palliative care. The main questions this study aims to answer are: * Does use of SUPPORT+ help maintain or improve health-related quality of life compared with usual palliative care? * Does SUPPORT+ reduce functional decline and acute health care use, such as hospitalisations, compared with usual care? Researchers will compare patients using the SUPPORT+ mobile application with patients receiving usual palliative care to see if digital symptom monitoring combined with automated self-management guidance and nurse follow-up improves patient-reported and clinical outcomes. Participants assigned to the SUPPORT+ arm will: * Use the SUPPORT+ mobile application for weekly symptom reporting using the Integrated Palliative Care Outcome Scale (IPOS) * Receive automated self-management advice based on reported symptoms * Receive follow-up contact from a nurse when severe or concerning symptoms are identified * Continue to receive usual palliative care throughout the study period Participants assigned to the usual care arm will: * Receive usual palliative care provided by their clinical team * Complete study assessments at scheduled time points * Not receive digital symptom monitoring, automated self-management advice, or nurse follow-up through the SUPPORT+ application
Conditions: Palliative Care, Advanced Cancer
Eligibility Criteria
Inclusion Criteria
- Adults aged 18 years or older
- Diagnosis of advanced malignancy
- Decision not to pursue further systemic anticancer treatment
- Receiving follow-up care at a participating palliative care clinic
- Community-dwelling
- Ownership of a smartphone
- Adequate cognitive capacity to provide informed consent
- Willingness to receive notifications from the SUPPORT+ mobile application
- Presence of at least one symptom related to advanced cancer
- Ability for the patient or a designated primary caregiver to use the mobile application
Exclusion Criteria
- Receiving systemic anticancer therapy with radical or palliative intent
- Estimated life expectancy of less than 3 months
- Eastern Cooperative Oncology Group (ECOG) performance status greater than 3
Eligibility criteria are kept as the original English records from ClinicalTrials.gov; actual eligibility is determined by the research team's formal assessment and the informed consent form. Source: ClinicalTrials.gov, updated automatically every two weeks. Last synced: 2026年10月8日.