血液中游離循環腫瘤DNA（crDNA）的發現以及ctDNA分析技術的成熟，為微創「液體活檢」基因診斷帶來了極具吸引力的機遇。研究人員計劃對胃腸道癌症患者進行EUS引導下門靜脈及肝靜脈抽吸。
適應症：Circulating Tumor Cell、Gastrointestinal Cancer
收案條件
納入條件
- Age \>= 18 years old
- Newly diagnosed stage II-IV distal gastric cancer, pancreatic cancer or colorectal cancer
- Undergoing treatment with either:
- Surgery
- Neoadjuvant chemotherapy
- Neoadjuvant chemoirradiation
- Palliative chemotherapy/ immunotherapy
排除條件
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- Synchronous cancer of other sites
- Cardia, high lesser curve tumors, oesophagogastric junction tumors
- Presence of bulky lymph nodes at lesser curve/ coeliac region precluding a clear EUS puncture site to portal vein and hepatic vein
- Patients with coagulopathy (international normalized ratio \>1.3, partial thromboplastin time greater than twice that of control), platelet count \<50,000x103/uL
- Patients unwilling to undergo follow-up assessments
- Patients with liver cirrhosis, portal hypertension and/ or gastric varices
- Patient refusal to participate
收案條件維持 ClinicalTrials.gov 原始英文登錄資料，實際收案資格以研究團隊的正式評估與受試者同意書為準。資料來源：ClinicalTrials.gov，每兩週自動更新，最後同步：2026年10月8日。