甲状腺结节是一种常见的疾病，影响多达60 ％的人口。估计发生甲状腺结节的终生概率为10 ％。虽然大多数甲状腺结节是良性的，但高达10-15%的结节会扩大，导致压迫性症状，包括颈部压力和不适、吞咽困难、呼吸困难和发音困难。这些良性但有问题的结节的传统治疗方法是甲状腺切除术。
适应症：Thyroid Nodule \(Benign\)、Ablation Therapy
入组条件
纳入标准
- Adult patients \>/=18 years of age
- Nodule maximal diameter ≥2cm and nodule volume \<20ml
- Nodule being predominantly solid (≥80% solid)
- Confirmed benign nature of nodules, either by : two benign fine needle biopsies, with the most recent biopsy performed within 1 year of enrollment in study or one benign fine needle biopsy and low suspicion characteristics on ultrasound
- Both functional and non-functional nodules are eligible.
排除标准
- Cytologically indeterminate nodules
- Nodules with substernal extension or posterior extension that cannot be viewed sufficiently with ultrasound
- current pregnancy or cardiac arrhythmias; presence of pacemaker or any medical condition that renders patient unfit for thermal ablation
入组条件维持 ClinicalTrials.gov 原始英文登记资料，实际入组资格以研究团队的正式评估与受试者知情同意书为准。资料来源：ClinicalTrials.gov，每两周自动更新，最后同步：2026年10月8日。