这是一项随机双盲对照试验，研究补充维生素D对多囊卵巢综合症（PCOS）女性排卵率的影响，以及治疗一年后的其他生殖、内分泌及代谢结局。
适应症：Polycystic Ovary Syndrome、Anovulation
入组条件
纳入标准
- Premenopausal
- Aged 18-40 years
- Irregular long menstrual cycles (\>35 days)
- PCOS according to the Rotterdam criteria
- Agree for transvaginal ultrasound
排除标准
- Use of hormonal medication (including contraception) within 3 months prior to study inclusion, except the use of a progestogen to induce withdrawal bleeding every 3 months
- History of any medical condition or medications that may predispose to vitamin D sensitivity, altered vitamin D metabolism and/ or hypercalcemia, including active tuberculosis or current therapy for tuberculosis, sarcoidosis, history of renal/ ureteral stones, parathyroid disease, renal or liver failure or current use of anti-convulsants
- Use of insulin-sensitizing drugs, lipid lowering drugs or anti-hypertensive
- Anticipated to use the above medications in the coming one year
- Known type 2 diabetes mellitus
- Refusal to join the study
- Abnormal blood calcium level
- For those on supplements, we asked them to stop their own supplements.
入组条件维持 ClinicalTrials.gov 原始英文登记资料，实际入组资格以研究团队的正式评估与受试者知情同意书为准。资料来源：ClinicalTrials.gov，每两周自动更新，最后同步：2026年10月8日。