暂停 NCT04025515

分子图谱分析项目

非小细胞肺癌不适用PD-L1

在本研究中,研究人员计划对肺癌标本中的「可操作」变异进行全面的分子图谱分析,以确定本地人群中每种基因亚型的患病率。

适应症:Lung Cancer、Non-Small Cell Lung Cancer

入组条件

纳入标准

  • The availability of sufficient archival tumor tissue specimen (15 slides of 4 microns per section)
  • Age ≥ 21 years
  • WHO performance status ≤ 2
  • Life expectancy of ≥ 12 weeks
  • Patients should have adequate organ function for potential consideration into clinical trials (routine blood tests are valid within 14 days before enrollment):
  • Adequate bone marrow function as shown by: ANC ≥ 1.0 x 10\^9/L, Platelets ≥ 75 x 10\^9/L, Hb ≥ 7.5 g/dL
  • Alanine aminotransferase (ALT) and aspirate aminotransferase (AST) normal range (or ≤3.0 x ULN if liver metastases are present)
  • Willing to provide signed informed consent
  • Patients whom do not fulfill the above criteria may be discussed on a case-by-case basis with the study team, for potential enrolment

排除标准

  • \- No more than 3 lines of cytotoxic chemotherapy at the time of enrolment

入组条件维持 ClinicalTrials.gov 原始英文登记资料,实际入组资格以研究团队的正式评估与受试者知情同意书为准。资料来源:ClinicalTrials.gov,每两周自动更新,最后同步:2026年10月8日。