局部前列腺癌的常规治疗选择包括前列腺切除术、放射治疗及积极监测。然而,前列腺切除术及放射治疗均有一定程度的并发症,包括尿失禁、勃起功能障碍及邻近结构损伤的风险。积极监测则带有疾病进展及患者心理困扰的风险。
适应症:Prostate Cancer
入组条件
纳入标准
- Visible index lesion(s) on MRI
- Index lesion(s) greater than 0.5 cm3
- Found to have localized low-risk or intermediate-risk prostate cancer after MRI-USG fusion targeted biopsy and saturation biopsy:
- Clinical tumour stage T2, or
- Gleason score 7, or
- PSA 20 ng/ml
排除标准
- Prostate size larger than 50 ml
- Patients unfit for contrast MRI exam
- Patients with previous treatment of prostate cancer
- Patients with previous surgery on the prostate
- Patients with active urinary tract infection
- Patients with bladder pathology including bladder stone and bladder cancer
- Patients with urethral stricture
- Patients with neurogenic bladder and/or sphincter abnormalities
- Fail to give informed consent
入组条件维持 ClinicalTrials.gov 原始英文登记资料,实际入组资格以研究团队的正式评估与受试者知情同意书为准。资料来源:ClinicalTrials.gov,每两周自动更新,最后同步:2026年11月5日。