已终止 NCT03927924

高强度聚焦超声研究

前列腺癌膀胱癌/尿路上皮癌不适用

局部前列腺癌的常规治疗选择包括前列腺切除术、放射治疗及积极监测。然而,前列腺切除术及放射治疗均有一定程度的并发症,包括尿失禁、勃起功能障碍及邻近结构损伤的风险。积极监测则带有疾病进展及患者心理困扰的风险。

适应症:Prostate Cancer

入组条件

纳入标准

  • Visible index lesion(s) on MRI
  • Index lesion(s) greater than 0.5 cm3
  • Found to have localized low-risk or intermediate-risk prostate cancer after MRI-USG fusion targeted biopsy and saturation biopsy:
  • Clinical tumour stage T2, or
  • Gleason score 7, or
  • PSA 20 ng/ml

排除标准

  • Prostate size larger than 50 ml
  • Patients unfit for contrast MRI exam
  • Patients with previous treatment of prostate cancer
  • Patients with previous surgery on the prostate
  • Patients with active urinary tract infection
  • Patients with bladder pathology including bladder stone and bladder cancer
  • Patients with urethral stricture
  • Patients with neurogenic bladder and/or sphincter abnormalities
  • Fail to give informed consent

入组条件维持 ClinicalTrials.gov 原始英文登记资料,实际入组资格以研究团队的正式评估与受试者知情同意书为准。资料来源:ClinicalTrials.gov,每两周自动更新,最后同步:2026年11月5日。